Clinical application of therapeutic drug monitoring(TDM).
نویسندگان
چکیده
منابع مشابه
Alternative calibration strategies for the clinical laboratory: application to nortriptyline therapeutic drug monitoring.
BACKGROUND The addition of a calibration curve with every run is both time-consuming and expensive for clinical mass spectrometry assays. We present alternative calibration strategies that eliminate the need for a calibration curve except as required by laboratory regulations. METHODS We measured serum nortriptyline concentrations prospectively in 68 patients on 16 days over a 2-month period ...
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Herein, gold nanoparticle had been successfully synthesized through a simple, inexpensive and clean electrochemical technique. Gold nanoparticles were directly deposited on the electrode surface using an electrochemical strategy. Then, the electrochemical deposition parameters (such as applied potential and deposition time) were optimized. 1.1 V and 250 s were applied as the optimal electrodepo...
متن کاملClinical efficacy of therapeutic drug monitoring in patients receiving vancomycin.
Efficacy of therapeutic drug monitoring (TDM) of vancomycin (VCM) was retrospectively investigated in 184 patients with methicillin-resistant Staphylococcus aureus (MRSA) infection. The incidence of nephrotoxicity was compared between the patients who received TDM practice (TDM group, n=73) and did not (non-TDM group, n=111). Creatinine clearance (CLcr) values decreased significantly after the ...
متن کاملTherapeutic Drug Concentrations of Teicoplanin in Clinical Settings
BACKGROUND Teicoplanin is a glycopeptide antibiotic that is widely used in clinical practice for the treatment of infections caused by drug-resistant Gram-positive bacteria. The aim of this study was to analyze plasma teicoplanin concentrations to determine the percentage of patients in whom therapeutic concentrations of teicoplanin were achieved in clinical practice. MATERIALS AND METHODS Th...
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ژورنال
عنوان ژورنال: Journal of Nippon Medical School
سال: 1992
ISSN: 0048-0444,1884-0108
DOI: 10.1272/jnms1923.59.2